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Goat Anti-APOB Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-APOB Antibody AF1076a
    AF1076a (0.5 µg/ml) staining of Human Serum lysates. Data kindly provided by Yan Xie and NO Davidson, Washington USA. This antibody showed background below 150kDa in serum samples . We call for caution when used for other assays than Western blot.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04114
Other Accession NP_000375, 338
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 515605 Da
Additional Information
Gene ID 338
Other Names Apolipoprotein B-100, Apo B-100, Apolipoprotein B-48, Apo B-48, APOB
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-APOB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
Cellular Location Cytoplasm. Secreted
Research Areas
Citations (0)

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This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.


ApoB genetic variants modify the response to fenofibrate: a GOLDN study. Wojczynski MK, et al. J Lipid Res, 2010 Aug 19. PMID 20724655.
Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients. Hu M, et al. Pharmacogenet Genomics, 2010 Oct. PMID 20679960.
A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). Romero R, et al. Am J Obstet Gynecol, 2010 Jul 29. PMID 20673868.
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. Johansen CT, et al. Nat Genet, 2010 Aug. PMID 20657596.
[Distribution characteristics of ApoB3'VNTR and hyperlipemia correlation factors in civil aircrew] Zhu F, et al. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi, 2010 Mar. PMID 20635694.

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$ 325.00
Cat# AF1076a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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