|Application ||WB, E|
|Other Accession||NP_006780, 10930, 11811 (mouse), 301226 (rat)|
|Calculated MW||25703 Da|
|Other Names||Probable C->U-editing enzyme APOBEC-2, 3.5.4.-, APOBEC2|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-APOBEC2 (aa12 - 26) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.|
|Tissue Location||Expressed exclusively in heart and skeletal muscle|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Microarray analysis of tonsils in immunoglobulin A nephropathy patients. Iio K, et al. Biochem Biophys Res Commun, 2010 Mar 19. PMID 20138841.
APOBEC deaminases-mutases with defensive roles for immunity. Prochnow C, et al. Sci China C Life Sci, 2009 Oct. PMID 19911124.
Gender differences in genetic risk profiles for cardiovascular disease. Silander K, et al. PLoS One, 2008. PMID 18974842.
The APOBEC-2 crystal structure and functional implications for the deaminase AID. Prochnow C, et al. Nature, 2007 Jan 25. PMID 17187054.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
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