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Goat Anti-APOBEC2 (aa180 - 190) Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-APOBEC2 (aa180 - 190) Antibody AF1078b
    AF1078b (1 µg/ml) staining of Human Muscle lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9Y235
Other Accession NP_006780, 10930, 11811 (mouse), 301226 (rat)
Reactivity Human
Predicted Mouse, Rat, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 25703 Da
Additional Information
Gene ID 10930
Other Names Probable C->U-editing enzyme APOBEC-2, 3.5.4.-, APOBEC2
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-APOBEC2 (aa180 - 190) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name APOBEC2
Function Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Tissue Location Expressed exclusively in heart and skeletal muscle.
Research Areas
Citations (0)
citation

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References

Microarray analysis of tonsils in immunoglobulin A nephropathy patients. Iio K, et al. Biochem Biophys Res Commun, 2010 Mar 19. PMID 20138841.
APOBEC deaminases-mutases with defensive roles for immunity. Prochnow C, et al. Sci China C Life Sci, 2009 Oct. PMID 19911124.
Gender differences in genetic risk profiles for cardiovascular disease. Silander K, et al. PLoS One, 2008. PMID 18974842.
The APOBEC-2 crystal structure and functional implications for the deaminase AID. Prochnow C, et al. Nature, 2007 Jan 25. PMID 17187054.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.

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$ 341.00
Cat# AF1078b
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