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APOBEC3G AntibodyPeptide-affinity purified goat antibody

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AF1080a 0.1mg 400 ul 7-10 days $ 325.00 Add to cart
  • Specification
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  • Backgrounds

APOBEC3G Antibody - Product info

Other AccessionNP_068594
ReactivityHuman
Concentration100ug/200ul
IsotypeIgG

APOBEC3G Antibody - Additional info

Other Names
APOBEC3G; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G; ARP9; CEM15; FLJ12740; MDS019; bK150C2.7; dJ494G10.1 ; DNA dC->dU editing enzyme; OTTHUMP00000028911; apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3G; phorbolin-like protein MDS019
Format
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
APOBEC3G Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.

REFERENCES

A critical function of toll-like receptor-3 in the induction of anti-human immunodeficiency virus activities in macrophages. Zhou Y, et al. Immunology, 2010 Sep. PMID 20636339. Identification of a critical T(Q/D/E)x5ADx2(I/L) motif from primate lentivirus Vif proteins that regulate APOBEC3G and APOBEC3F neutralizing activity. Dang Y, et al. J Virol, 2010 Sep. PMID 20592083. Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis. Vartanian JP, et al. PLoS Pathog, 2010 May 27. PMID 20523896. APOBEC3G contributes to HIV-1 variation through sublethal mutagenesis. Sadler HA, et al. J Virol, 2010 Jul. PMID 20463080. APOBEC3G generates nonsense mutations in human T-cell leukemia virus type 1 proviral genomes in vivo. Fan J, et al. J Virol, 2010 Jul. PMID 20463074.