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Goat Anti-Arylsulfatase A Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-Arylsulfatase A Antibody AF1113a
    AF1113a (0.5 µg/ml) staining of Mouse Testis lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P15289
Other Accession NP_000478, 410, 11883 (mouse), 315222 (rat)
Reactivity Mouse
Predicted Human, Rat
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 53588 Da
Additional Information
Gene ID 410
Other Names Arylsulfatase A, ASA,, Cerebroside-sulfatase, Arylsulfatase A component B, Arylsulfatase A component C, ARSA
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Arylsulfatase A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Hydrolyzes cerebroside sulfate.
Cellular Location Lysosome.
Research Areas
Citations (0)

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The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Multiple alternatively spliced transcript variants, one of which encodes a distinct protein, have been described for this gene.


Characterization of new arylsulfatase A gene mutations reinforces genotype-phenotype correlation in metachromatic leukodystrophy. Cesani M, et al. Hum Mutat, 2009 Oct. PMID 19606494.
Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19. Oshikawa M, et al. Mol Vis, 2009. PMID 19262745.
Saposin B-dependent reconstitution of arylsulfatase A activity in vitro and in cell culture models of metachromatic leukodystrophy. Matzner U, et al. J Biol Chem, 2009 Apr 3. PMID 19224915.
Chromosomal deletion unmasking a recessive disease: 22q13 deletion syndrome and metachromatic leukodystrophy. Bisgaard AM, et al. Clin Genet, 2009 Feb. PMID 19054018.
Molecular and clinical consequences of novel mutations in the arylsulfatase A gene. 艁ugowska A, et al. Clin Genet, 2009 Jan. PMID 19021637.

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$ 325.00
Cat# AF1113a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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