|Application ||WB, E|
|Other Accession||NP_033667, 414|
|Calculated MW||64860 Da|
|Other Names||Arylsulfatase D, ASD, 3.1.6.-, ARSD|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Arylsulfatase D Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expressed in the pancreas, kidney, liver, lung, placenta, brain and heart|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the sulfatase family. Sulfatases are essential for the correct composition of bone and cartilage matrix. This encoded protein is postranslationally glycosylated and localized to the lysosome. Two transcript variants encoding different isoforms have been found for this gene.
Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
Arylsulfatase D gene in Xp22.3 encodes two protein isoforms. Urbitsch P, et al. DNA Cell Biol, 2000 Dec. PMID 11177574.
Expression profiling of human sulfotransferase and sulfatase gene superfamilies in epithelial tissues and cultured cells. Dooley TP, et al. Biochem Biophys Res Commun, 2000 Oct 14. PMID 11027669.
Characterization of a cluster of sulfatase genes on Xp22.3 suggests gene duplications in an ancestral pseudoautosomal region. Meroni G, et al. Hum Mol Genet, 1996 Apr. PMID 8845834.
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