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Goat Anti-AVPR1B Antibody

Peptide-affinity purified goat antibody

  • IHC - Goat Anti-AVPR1B Antibody AF1129b
    AF1129b (5 µg/ml) staining of paraffin embedded Human Anterior Pituitary Gland. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
  • WB - Goat Anti-AVPR1B Antibody AF1129b
    AF1129b (0.5 µg/ml) staining of Human Amygdala lysate (35 µg protein in RIPA buffer) in lane A and AF1129a (0.05 µg/ml) staining of Rat Brain lysate (35 µg protein in RIPA buffer) in lane B . Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P47901
Other Accession NP_000698, 553
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 46971 Da
Additional Information
Gene ID 553
Other Names Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor, AVPR1B, AVPR3, VPR3
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-AVPR1B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms AVPR3, VPR3
Function Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.


Associations between common arginine vasopressin 1b receptor and glucocorticoid receptor gene variants and HPA axis responses to psychosocial stress in a child psychiatric population. van West D, et al. Psychiatry Res, 2010 Aug 30. PMID 20472303.
Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. Binder EB, et al. Arch Gen Psychiatry, 2010 Apr. PMID 20368512.
Poor replication of candidate genes for major depressive disorder using genome-wide association data. Bosker FJ, et al. Mol Psychiatry, 2010 Mar 30. PMID 20351714.
Genetical genomic determinants of alcohol consumption in rats and humans. Tabakoff B, et al. BMC Biol, 2009 Oct 27. PMID 19874574.
Arginine vasopressin receptor gene-based single-nucleotide polymorphism analysis in attention deficit hyperactivity disorder. van West D, et al. Psychiatr Genet, 2009 Apr. PMID 19668115.

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$ 325.00
Cat# AF1129b
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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