|Application ||WB, E|
|Other Accession||NP_006568, 10678, 53625 (mouse)|
|Calculated MW||46022 Da|
|Other Names||N-acetyllactosaminide beta-1, 3-N-acetylglucosaminyltransferase 2, 22.214.171.124, Beta-1, 3-N-acetylglucosaminyltransferase 1, BGnT-1, Beta-1, 3-Gn-T1, Beta3Gn-T1, Beta-1, 3-galactosyltransferase 7, Beta-1, 3-GalTase 7, Beta3Gal-T7, Beta3GalT7, b3Gal-T7, Beta-3-Gx-T7, UDP-Gal:beta-GlcNAc beta-1, 3-galactosyltransferase 7, UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 2, BGnT-2, Beta-1, 3-Gn-T2, Beta-1, 3-N-acetylglucosaminyltransferase 2, Beta3Gn-T2, UDP-galactose:beta-N-acetylglucosamine beta-1, 3-galactosyltransferase 7, B3GNT2, B3GALT7, B3GNT1|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-B3GNT2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed:9892646). Probably constitutes the main polylactosamine synthase.|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains.
Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Australo-Anglo-American Spondyloarthritis Consortium (TASC), et al. Nat Genet, 2010 Feb. PMID 20062062.
Activation of beta1,3-N-acetylglucosaminyltransferase-2 (beta3Gn-T2) by beta3Gn-T8. Possible involvement of beta3Gn-T8 in increasing poly-N-acetyllactosamine chains in differentiated HL-60 cells. Seko A, et al. J Biol Chem, 2008 Nov 28. PMID 18826941.
Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. Liu T, et al. J Proteome Res, 2005 Nov-Dec. PMID 16335952.
Characterization of a cDNA encoding a protein with limited similarity to beta1, 3-N-acetylglucosaminyltransferase. Zheng H, et al. Mol Biol Rep, 2004 Sep. PMID 15560372.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
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