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Goat Anti-B5 Receptor / PCID1 / EIF3M Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-B5 Receptor / PCID1 / EIF3M Antibody AF1132a
    AF1132a (0.1 µg/ml) staining of A549 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • IHC - Goat Anti-B5 Receptor / PCID1 / EIF3M Antibody AF1132a
    AF1132a (5 µg/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7L2H7
Other Accession NP_006351, 10480, 98221 (mouse), 295975 (rat)
Reactivity Human
Predicted Mouse, Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 42503 Da
Additional Information
Gene ID 10480
Other Names Eukaryotic translation initiation factor 3 subunit M {ECO:0000255|HAMAP-Rule:MF_03012}, eIF3m {ECO:0000255|HAMAP-Rule:MF_03012}, Fetal lung protein B5, hFL-B5, PCI domain-containing protein 1, EIF3M {ECO:0000255|HAMAP-Rule:MF_03012}, HFLB5, PCID1
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-B5 Receptor / PCID1 / EIF3M Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EIF3M {ECO:0000255|HAMAP-Rule:MF_03012}
Synonyms HFLB5, PCID1
Function Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2).
Cellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03012}.
Tissue Location Broadly expressed.
Research Areas
Citations (0)

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HFLB5 encodes a broadly expressed protein containing putative membrane fusion domains that acts as a receptor or coreceptor for entry of herpes simplex virus (HSV) (Perez et al., 2005 [PubMed 15919898]).


Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.
Genome-wide silencing in Drosophila captures conserved apoptotic effectors. Chew SK, et al. Nature, 2009 Jul 2. PMID 19483676.
Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. Lasky-Su J, et al. Am J Med Genet B Neuropsychiatr Genet, 2008 Dec 5. PMID 18821565.
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3. Zhou M, et al. Proc Natl Acad Sci U S A, 2008 Nov 25. PMID 18599441.

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$ 325.00
Cat# AF1132a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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