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Goat Anti-BMYB / MYBL2 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-BMYB / MYBL2 Antibody AF1161a
    AF1161a (0.1 µg/ml) staining of rat stomach lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P10244
Other Accession NP_002457, 4605, 17865 (mouse), 296344 (rat)
Reactivity Rat
Predicted Human, Mouse, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 78764 Da
Additional Information
Gene ID 4605
Other Names Myb-related protein B, B-Myb, Myb-like protein 2, MYBL2, BMYB
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-BMYB / MYBL2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MYBL2
Synonyms BMYB
Function Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.
Cellular Location Nucleus.
Research Areas
Citations (0)

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The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.


Focal amplifications are associated with high grade and recurrences in stage Ta bladder carcinoma. Nord H, et al. Int J Cancer, 2010 Mar 15. PMID 19821490.
Genetic susceptibility to distinct bladder cancer subphenotypes. Guey LT, et al. Eur Urol, 2010 Feb. PMID 19692168.
PTEN identified as important risk factor of chronic obstructive pulmonary disease. Hosgood HD 3rd, et al. Respir Med, 2009 Dec. PMID 19625176.
B-MYB is required for recovery from the DNA damage-induced G2 checkpoint in p53 mutant cells. Mannefeld M, et al. Cancer Res, 2009 May 1. PMID 19383908.
Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. Shen M, et al. Environ Mol Mutagen, 2009 May. PMID 19170196.

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$ 325.00
Cat# AF1161a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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