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Goat Anti-CDK10 / PISSLRE Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-CDK10 / PISSLRE Antibody AF1221a
    AF1221a (2 µg/ml) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15131
Other Accession NP_443714, 8558
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 41038 Da
Additional Information
Gene ID 8558
Other Names Cyclin-dependent kinase 10,, Cell division protein kinase 10, Serine/threonine-protein kinase PISSLRE, CDK10
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-CDK10 / PISSLRE Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDK10
Function Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells).
Research Areas
Citations (0)

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The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene.


CDK10 is not a target for aberrant DNA methylation in breast cancer. Heller G, et al. Anticancer Res, 2009 Oct. PMID 19846932.
Genome-wide association study identifies three loci associated with melanoma risk. Bishop DT, et al. Nat Genet, 2009 Aug. PMID 19578364.
A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. Han J, et al. PLoS Genet, 2008 May 16. PMID 18483556.
Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer. Iorns E, et al. Cancer Cell, 2008 Feb. PMID 18242510.
Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry. Wissing J, et al. Mol Cell Proteomics, 2007 Mar. PMID 17192257.

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$ 325.00
Cat# AF1221a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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