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Goat Anti-CENTA1 Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-CENTA1 Antibody AF1226a
    AF1226a (1 µg/ml) staining of Human Brain lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O75689
Other Accession NP_006860, 11033, 231821 (mouse), 171097 (rat)
Reactivity Human, Mouse
Predicted Rat, Pig, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5mg/ml
Isotype IgG
Calculated MW 43395 Da
Additional Information
Gene ID 11033
Other Names Arf-GAP with dual PH domain-containing protein 1, Centaurin-alpha-1, Cnt-a1, Putative MAPK-activating protein PM25, ADAP1, CENTA1
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-CENTA1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADAP1
Synonyms CENTA1
Function GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).
Cellular Location Nucleus. Cytoplasm. Note=Recruited to the plasma membrane upon epidermal growth factor-dependent activation of phosphatidylinositol 4,5-diphosphate (PtdInsP2) 3-kinase
Tissue Location Expressed at highest levels in brain and at lower levels in peripheral blood leukocytes.
Research Areas
Citations (0)
citation

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References

Polymorphisms in innate immunity genes and risk of childhood leukemia. Han S, et al. Hum Immunol, 2010 Jul. PMID 20438785. Risk of meningioma and common variation in genes related to innate immunity. Rajaraman P, et al. Cancer Epidemiol Biomarkers Prev, 2010 May. PMID 20406964. Common variation in genes related to innate immunity and risk of adult glioma. Rajaraman P, et al. Cancer Epidemiol Biomarkers Prev, 2009 May. PMID 19423540. RanBPM, a novel interaction partner of the brain-specific protein p42IP4/centaurin alpha-1. Haase A, et al. J Neurochem, 2008 Jun 1. PMID 18298663. Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.

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$ 341.00
Cat# AF1226a
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