|Application ||WB, E|
|Other Accession||NP_006860, 11033, 231821 (mouse), 171097 (rat)|
|Predicted||Rat, Pig, Dog|
|Calculated MW||43395 Da|
|Other Names||Arf-GAP with dual PH domain-containing protein 1, Centaurin-alpha-1, Cnt-a1, Putative MAPK-activating protein PM25, ADAP1, CENTA1|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-CENTA1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).|
|Cellular Location||Nucleus. Cytoplasm. Note=Recruited to the plasma membrane upon epidermal growth factor-dependent activation of phosphatidylinositol 4,5-diphosphate (PtdInsP2) 3-kinase|
|Tissue Location||Expressed at highest levels in brain and at lower levels in peripheral blood leukocytes|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Polymorphisms in innate immunity genes and risk of childhood leukemia. Han S, et al. Hum Immunol, 2010 Jul. PMID 20438785. Risk of meningioma and common variation in genes related to innate immunity. Rajaraman P, et al. Cancer Epidemiol Biomarkers Prev, 2010 May. PMID 20406964. Common variation in genes related to innate immunity and risk of adult glioma. Rajaraman P, et al. Cancer Epidemiol Biomarkers Prev, 2009 May. PMID 19423540. RanBPM, a novel interaction partner of the brain-specific protein p42IP4/centaurin alpha-1. Haase A, et al. J Neurochem, 2008 Jun 1. PMID 18298663. Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
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