Goat Anti-CENTB1 / ACAP1 Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q15027 |
Other Accession | NP_055531, 9744, 216859 (mouse) |
Reactivity | Human |
Predicted | Mouse, Rat, Dog, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 100ug/200ul |
Isotype | IgG |
Calculated MW | 81536 Da |
Gene ID | 9744 |
---|---|
Other Names | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1, Centaurin-beta-1, Cnt-b1, ACAP1, CENTB1, KIAA0050 |
Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-CENTB1 / ACAP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ACAP1 |
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Synonyms | CENTB1, KIAA0050 |
Function | GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration. |
Cellular Location | Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side |
Tissue Location | Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas. |
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Provided below are standard protocols that you may find useful for product applications.
References
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Substrate specificities and activities of AZAP family Arf GAPs in vivo. Cuthbert EJ, et al. Am J Physiol Cell Physiol, 2008 Jan. PMID 18003747.
An ACAP1-containing clathrin coat complex for endocytic recycling. Li J, et al. J Cell Biol, 2007 Jul 30. PMID 17664335.
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. Wu C, et al. Proteomics, 2007 Jun. PMID 17474147.
Cooperation of phosphoinositides and BAR domain proteins in endosomal tubulation. Shinozaki-Narikawa N, et al. Traffic, 2006 Nov. PMID 17010122.
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