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Goat Anti-CLEC2 / CLEC1B Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-CLEC2 / CLEC1B Antibody AF1248a
    AF1248a (1 µg/ml) staining of human kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P126
Other Accession NP_057593, 51266
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 26596 Da
Additional Information
Gene ID 51266
Other Names C-type lectin domain family 1 member B, C-type lectin-like receptor 2, CLEC-2, CLEC1B, CLEC2
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-CLEC2 / CLEC1B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CLEC2
Cellular Location Membrane; Single-pass type II membrane protein
Tissue Location Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.
Research Areas
Citations (0)

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Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells.


Genome-wide searching of rare genetic variants in WTCCC data. Feng T, et al. Hum Genet, 2010 Sep. PMID 20549515.
Incorporation of podoplanin into HIV released from HEK-293T cells, but not PBMC, is required for efficient binding to the attachment factor CLEC-2. Chaipan C, et al. Retrovirology, 2010 May 19. PMID 20482880.
New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.
CLEC-2 activates Syk through dimerization. Hughes CE, et al. Blood, 2010 Apr 8. PMID 20154219.
Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization, secondary mediators, and Rac. Pollitt AY, et al. Blood, 2010 Apr 8. PMID 20154214.

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$ 325.00
Cat# AF1248a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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