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Goat Anti-CRP2 / CSRP2 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-CRP2 / CSRP2 Antibody AF1278a
    AF1278a (0.1 µg/ml) staining of mouse kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • WB - Goat Anti-CRP2 / CSRP2 Antibody AF1278a
    HEK293 overexpressing CRP2 (RC201565) and probed with AF1278a (mock transfection in first lane), tested by Origene.
  • IHC - Goat Anti-CRP2 / CSRP2 Antibody AF1278a
    AF1278a (3.8 µg/ml) staining of paraffin embedded Human Lung. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16527
Other Accession NP_001312, 1466, 13008 (mouse)
Reactivity Human, Mouse, Rat
Predicted Horse
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 20954 Da
Additional Information
Gene ID 1466
Other Names Cysteine and glycine-rich protein 2, Cysteine-rich protein 2, CRP2, LIM domain only protein 5, LMO-5, Smooth muscle cell LIM protein, SmLIM, CSRP2, LMO5, SMLIM
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-CRP2 / CSRP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSRP2
Synonyms LMO5, SMLIM
Function Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.
Cellular Location Nucleus.
Tissue Location Highly expressed in the aorta, but not in heart and skeletal muscle
Research Areas
Citations (0)

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CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3.


The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
Interleukin-10 activation of the interleukin-10E1 pathway and tissue inhibitor of metalloproteinase-1 expression is enhanced by proteasome inhibitors in primary prostate tumor lines. Stearns ME, et al. Mol Cancer Res, 2003 Jul. PMID 12861049.
IL-10/IL-10 receptor signaling regulates TIMP-1 expression in primary human prostate tumor lines. Wang M, et al. Cancer Biol Ther, 2002 Sep-Oct. PMID 12496489.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1. Weiskirchen R, et al. Biochem J, 2001 Nov 1. PMID 11672422.

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$ 325.00
Cat# AF1278a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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