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Goat Anti-CSNK1E Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-CSNK1E Antibody AF1282a
    HEK293 overexpressing CSNK1E (RC202436) and probed with AF1282a (mock transfection in first lane), tested by Origene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P49674
Other Accession NP_689407, 1454, 27373 (mouse), 58822 (rat)
Reactivity Human
Predicted Mouse, Rat, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 47315 Da
Additional Information
Gene ID 102800317;1454
Other Names Casein kinase I isoform epsilon, CKI-epsilon, CKIe,, CSNK1E
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-CSNK1E Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine- induced granuloytic differentiation.
Cellular Location Cytoplasm. Nucleus
Tissue Location Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes
Research Areas
Citations (0)

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The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
Centrosome-related genes, genetic variation, and risk of breast cancer. Olson JE, et al. Breast Cancer Res Treat, 2010 May 28. PMID 20508983.
Systematic analysis of circadian genes in a population-based sample reveals association of TIMELESS with depression and sleep disturbance. Utge SJ, et al. PLoS One, 2010 Feb 18. PMID 20174623.
Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder. Soria V, et al. Neuropsychopharmacology, 2010 May. PMID 20072116.
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Zhao B, et al. Genes Dev, 2010 Jan 1. PMID 20048001.

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$ 325.00
Cat# AF1282a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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