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Goat Anti-DCDC2 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-DCDC2 Antibody AF1305a
    AF1305a (0.2 µg/ml) staining of COS7 cell lysate transfected with full length recombinant human DCDC2 (A) and untransfected control COS7 cells (B). Primary incubation was 1 hour. Detected by chemiluminescence.
  • IHC - Goat Anti-DCDC2 Antibody AF1305a
    AF1305a (5 µg/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UHG0
Other Accession NP_057440, 51473
Reactivity Human, Mouse, Rat
Predicted Pig, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 52834 Da
Additional Information
Gene ID 51473
Other Names Doublecortin domain-containing protein 2, Protein RU2S, DCDC2, KIAA1154, RU2
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-DCDC2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DCDC2
Synonyms KIAA1154, RU2
Function May be involved in neuronal migration during development of the cerebral neocortex.
Tissue Location Ubiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus
Research Areas
Citations (0)

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This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. Mutations in this gene have been associated with Reading Disability (RD), also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene.


The doublecortin gene family and disorders of neuronal structure. Dijkmans TF, et al. Cent Nerv Syst Agents Med Chem, 2010 Mar. PMID 20236041.
Dyslexia and DCDC2: normal variation in reading and spelling is associated with DCDC2 polymorphisms in an Australian population sample. Lind PA, et al. Eur J Hum Genet, 2010 Jun. PMID 20068590.
A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia. Meda SA, et al. Neuroimage, 2010 Nov 15. PMID 19944766.
Progress towards a cellular neurobiology of reading disability. Gabel LA, et al. Neurobiol Dis, 2010 May. PMID 19616627.
Association of reading disabilities with regions marked by acetylated H3 histones in KIAA0319. Couto JM, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Mar 5. PMID 19588467.

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$ 325.00
Cat# AF1305a
(40 western blots)
Availability: 7-10 days
Bulk Size
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