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Goat Anti-DEAD-box protein 6 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-DEAD-box protein 6 Antibody AF1312a
    AF1312a (0.3µg/ml) staining of Daudi (A), Jurkat (B) and HepG2 (C) lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P26196
Other Accession NP_004388, 1656
Reactivity Human
Predicted Mouse, Rat, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 54417 Da
Additional Information
Gene ID 1656
Other Names Probable ATP-dependent RNA helicase DDX6,, ATP-dependent RNA helicase p54, DEAD box protein 6, Oncogene RCK, DDX6, HLR2, RCK
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-DEAD-box protein 6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DDX6
Synonyms HLR2, RCK
Function In the process of mRNA degradation, may play a role in mRNA decapping.
Cellular Location Cytoplasm, P-body
Tissue Location Abundantly expressed in most tissues.
Research Areas
Citations (0)

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This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing.


DDX6 (Rck/p54) is required for efficient hepatitis C virus replication but not for internal ribosome entry site-directed translation. Jangra RK, et al. J Virol, 2010 Jul. PMID 20392846.
A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations. Lind PA, et al. Twin Res Hum Genet, 2010 Feb. PMID 20158304.
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Han JW, et al. Nat Genet, 2009 Nov. PMID 19838193.
Role of p54 RNA helicase activity and its C-terminal domain in translational repression, P-body localization and assembly. Minshall N, et al. Mol Biol Cell, 2009 May. PMID 19297524.
Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B. Tritschler F, et al. Mol Cell, 2009 Mar 13. PMID 19285948.

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$ 325.00
Cat# AF1312a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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