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Goat Anti-DGAT2 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-DGAT2 Antibody AF1316a
    AF1316a (0.5 µg/ml) staining of Human Liver lysate in the third lane (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • WB - Goat Anti-DGAT2 Antibody AF1316a
    HEK293 overexpressing DGAT2 (lane A) and probed with AF1316a (mock transfection in lane B).
  • IHC - Goat Anti-DGAT2 Antibody AF1316a
    AF1316a (3 µg/ml) staining of paraffin embedded Human Liver. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.
  • EIA - Goat Anti-DGAT2 Antibody AF1316a
    AF1316a (0.5ug/ml) as the reporter with AF1316a as the capture rabbit antibody (2.5ug/ml).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96PD7
Other Accession NP_115953, 84649, 67800 (mouse), 252900 (rat)
Reactivity Human
Predicted Mouse, Rat, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 43831 Da
Additional Information
Gene ID 84649
Other Names Diacylglycerol O-acyltransferase 2,, Acyl-CoA retinol O-fatty-acyltransferase, ARAT, Retinol O-fatty-acyltransferase,, Diglyceride acyltransferase 2, DGAT2
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-DGAT2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DGAT2
Function Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides (By similarity). Functions also as an acyl-CoA retinol acyltransferase (ARAT).
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet
Tissue Location Predominantly expressed in liver and white adipose tissue. Expressed at lower level in mammary gland, testis and peripheral blood leukocytes. Expressed in sebaceous glands of normal skin but decreased psoriatic skin
Research Areas
Citations (0)

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Acyl-CoA:diacylglycerol acyltransferase, or DGAT (EC, is responsible for the synthesis of triglycerides. It catalyzes a reaction in which diacylglycerol is covalently joined to long chain fatty acyl-CoAs.


Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients. Hu M, et al. Pharmacogenet Genomics, 2010 Oct. PMID 20679960.
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.
The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria. Stone SJ, et al. J Biol Chem, 2009 Feb 20. PMID 19049983.

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$ 325.00
Cat# AF1316a
(40 western blots)
Availability: 7-10 days
Bulk Size
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