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DKK4 AntibodyPeptide-affinity purified goat antibody
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AF1326a | 0.1mg 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
DKK4 Antibody - Product info | |
| Application | WB
|
| Other Accession | NP_055235 |
| Reactivity | Human |
| Concentration | 100ug/200ul |
| Isotype | IgG |
DKK4 Antibody - Additional info | |
| Other Names DKK4; dickkopf homolog 4 (Xenopus laevis); DKK-4; hdkk-4; Dickkopf gene 4; dickkopf (Xenopus laevis) homolog 4; MGC129562; MGC129563; dickkopf homolog 4 | |
| Dilution WB~~1:200~500 | |
| Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions DKK4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
DKK4 Antibody - Application data
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AF1326a staining (1 µg/ml) of Jurkat lysate (RIPA buffer, 30 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
DKK4 Antibody - Related products
AP11649b: DKK4 Antibody (C-term)
AP1524a: DKK4 Antibody (N-term)
AP1524b: DKK4 Antibody (C-term)
LY12023a: DKK4 Over-expression Lysate
BP1524a: DKK4 Antibody (N-term) Blocking Peptide
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BACKGROUND
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co-receptor and the co-factor kremen 2.
REFERENCES
Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. Hosgood HD 3rd, et al. Occup Environ Med, 2009 Dec. PMID 19773279. DICKKOPF-4 and -2 genes are upregulated in human colorectal cancer. Matsui A, et al. Cancer Sci, 2009 Oct. PMID 19659606. Wnt antagonist gene polymorphisms and renal cancer. Hirata H, et al. Cancer, 2009 Oct 1. PMID 19562778. High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Yerges LM, et al. J Bone Miner Res, 2009 Dec. PMID 19453261. Dickkopf-4 is frequently down-regulated and inhibits growth of colorectal cancer cells. Baehs S, et al. Cancer Lett, 2009 Apr 18. PMID 19059704.
