|Application ||WB, E|
|Other Accession||NP_004217, 9262|
|Calculated MW||42344 Da|
|Other Names||Serine/threonine-protein kinase 17B, 22.214.171.124, DAP kinase-related apoptosis-inducing protein kinase 2, STK17B, DRAK2|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-DRAK2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.|
|Cellular Location||Nucleus. Cell membrane. Endoplasmic reticulum-Golgi intermediate compartment. Note=Colocalizes with STK17B at the plasma membrane.|
|Tissue Location||Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors. Landa I, et al. PLoS Genet, 2009 Sep. PMID 19730683.
Regulation of the apoptosis-inducing kinase DRAK2 by cyclooxygenase-2 in colorectal cancer. Doherty GA, et al. Br J Cancer, 2009 Aug 4. PMID 19638987.
Altered thymic selection and increased autoimmunity caused by ectopic expression of DRAK2 during T cell development. Gatzka M, et al. J Immunol, 2009 Jul 1. PMID 19542440.
Modulation of DRAK2 autophosphorylation by antigen receptor signaling in primary lymphocytes. Friedrich ML, et al. J Biol Chem, 2007 Feb 16. PMID 17182616.
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