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Goat Anti-EndoPDI / TXNDC5 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-EndoPDI / TXNDC5 Antibody AF1367a
    AF1367a staining (0.1 µg/ml) of human placenta lysate (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NBS9
Other Accession NP_001139021, 81567
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 47629 Da
Additional Information
Gene ID 81567
Other Names Thioredoxin domain-containing protein 5, Endoplasmic reticulum resident protein 46, ER protein 46, ERp46, Thioredoxin-like protein p46, TXNDC5, TLP46
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-EndoPDI / TXNDC5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TLP46
Function Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast (By similarity).
Cellular Location Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}
Research Areas
Citations (0)

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This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Two transcript variants encoding different isoforms have been found for this gene.


The influence of TXNDC5 gene on gastric cancer cell. Zhang L, et al. J Cancer Res Clin Oncol, 2010 Oct. PMID 20157732.
ERp46 binds to AdipoR1, but not AdipoR2, and modulates adiponectin signalling. Charlton HK, et al. Biochem Biophys Res Commun, 2010 Feb 5. PMID 20074551.
Association of TXNDC5 gene polymorphisms and susceptibility to nonsegmental vitiligo in the Korean population. Jeong KH, et al. Br J Dermatol, 2010 Apr. PMID 19906073.
Protein disulphide isomerase family members show distinct substrate specificity: P5 is targeted to BiP client proteins. Jessop CE, et al. J Cell Sci, 2009 Dec 1. PMID 19887585.
Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. Wheeler HE, et al. PLoS Genet, 2009 Oct. PMID 19834535.

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$ 325.00
Cat# AF1367a
(40 western blots)
Availability: 7-10 days
Bulk Size
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