|Application ||WB, E|
|Other Accession||NP_036439, 23136|
|Predicted||Mouse, Rat, Dog|
|Calculated MW||120678 Da|
|Other Names||Band 4.1-like protein 3, 4.1B, Differentially expressed in adenocarcinoma of the lung protein 1, DAL-1, Band 4.1-like protein 3, N-terminally processed, EPB41L3, DAL1, KIAA0987|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-EPB41L3 / DAL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N- methyltransferases, including PRMT3 and PRMT5.|
|Cellular Location||Cytoplasm, cytoskeleton. Cell junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Detected in the cytoplasm of actively dividing cells|
|Tissue Location||Expressed at high levels in brain, with lower levels in kidney, intestine, and testis. Detected in lung|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
SynCAM1 recruits NMDA receptors via protein 4.1B. Hoy JL, et al. Mol Cell Neurosci, 2009 Dec. PMID 19796685.
A Golgi-associated protein 4.1B variant is required for assimilation of proteins in the membrane. Kang Q, et al. J Cell Sci, 2009 Apr 15. PMID 19299464.
Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. Martins-de-Souza D, et al. Eur Arch Psychiatry Clin Neurosci, 2009 Apr. PMID 19165527.
Frequent concomitant epigenetic silencing of the stress-responsive tumor suppressor gene CADM1, and its interacting partner DAL-1 in nasal NK/T-cell lymphoma. Fu L, et al. Int J Cancer, 2009 Apr 1. PMID 19115211.
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