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Goat Anti-ERG Antibody

Peptide-affinity purified goat antibody

  • IHC - Goat Anti-ERG Antibody AF1378a
    AF1378a (4 µg/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11308
Other Accession NP_001129627, 2078, 13876 (mouse), 170909 (rat)
Reactivity Human
Predicted Mouse, Rat
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 54608 Da
Additional Information
Gene ID 2078
Other Names Transcriptional regulator ERG, Transforming protein ERG, ERG
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-ERG Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ERG
Function Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00237, ECO:0000269|PubMed:17289661}. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs
Research Areas
Citations (0)

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Fluorescence-tracking of activation gating in human ERG channels reveals rapid S4 movement and slow pore opening. Es-Salah-Lamoureux Z, et al. PLoS One, 2010 May 28. PMID 20526358.
An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Yu J, et al. Cancer Cell, 2010 May 18. PMID 20478527.
Association of SPINK1 expression and TMPRSS2:ERG fusion with prognosis in endocrine-treated prostate cancer. Leinonen KA, et al. Clin Cancer Res, 2010 May 15. PMID 20442300.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Impact of EWS-ETS fusion type on disease progression in Ewing's sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-E.W.I.N.G. 99 trial. Le Deley MC, et al. J Clin Oncol, 2010 Apr 20. PMID 20308673.

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$ 325.00
Cat# AF1378a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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