|Application ||WB, E|
|Other Accession||NP_996318, 2104, 26381 (mouse)|
|Calculated MW||51306 Da|
|Other Names||Estrogen-related receptor gamma, ERR gamma-2, Estrogen receptor-related protein 3, Nuclear receptor subfamily 3 group B member 3, ESRRG, ERR3, ERRG2, KIAA0832, NR3B3|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-ESRRG Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ERR3, ERRG2, KIAA0832, NR3B3|
|Function||Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity). Induces the expression of PERM1 in the skeletal muscle.|
|Tissue Location||Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Identification and characterization of estrogen receptor-related receptor alpha and gamma in human glioma and astrocytoma cells. Gandhari MK, et al. Mol Cell Endocrinol, 2010 Feb 5. PMID 19822186.
Association with replication between estrogen-related receptor gamma (ESRRgamma) polymorphisms and bone phenotypes in women of European ancestry. Elfassihi L, et al. J Bone Miner Res, 2010 Apr. PMID 19821770.
Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. Xie YB, et al. J Biol Chem, 2009 Oct 16. PMID 19690166.
Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women. Sangrajrang S, et al. Int J Cancer, 2009 Aug 15. PMID 19415745.
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