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Goat Anti-ESRRG Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-ESRRG Antibody AF1383a
    AF1383a (0.2 µg/ml) staining of Human Breast lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
  • WB - Goat Anti-ESRRG Antibody AF1383a
    HEK293 overexpressing ESRRG (RC218233) and probed with AF1383a (mock transfection in first lane), tested by Origene.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P62508
Other Accession NP_996318, 2104, 26381 (mouse)
Reactivity Human
Predicted Mouse, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 51306 Da
Additional Information
Gene ID 2104
Other Names Estrogen-related receptor gamma, ERR gamma-2, Estrogen receptor-related protein 3, Nuclear receptor subfamily 3 group B member 3, ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-ESRRG Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ESRRG
Synonyms ERR3, ERRG2, KIAA0832, NR3B3
Function Orphan receptor that acts as a transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity). Induces the expression of PERM1 in the skeletal muscle.
Cellular Location Nucleus.
Tissue Location Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland
Research Areas
Citations (0)
citation

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References

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Identification and characterization of estrogen receptor-related receptor alpha and gamma in human glioma and astrocytoma cells. Gandhari MK, et al. Mol Cell Endocrinol, 2010 Feb 5. PMID 19822186.
Association with replication between estrogen-related receptor gamma (ESRRgamma) polymorphisms and bone phenotypes in women of European ancestry. Elfassihi L, et al. J Bone Miner Res, 2010 Apr. PMID 19821770.
Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. Xie YB, et al. J Biol Chem, 2009 Oct 16. PMID 19690166.
Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women. Sangrajrang S, et al. Int J Cancer, 2009 Aug 15. PMID 19415745.

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$ 341.00
Cat# AF1383a
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Availability: 7-10 days
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