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Goat Anti-EXOC7 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-EXOC7 Antibody AF1387a
    AF1387a (0.5 µg/ml) staining of Human Lung lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • IHC - Goat Anti-EXOC7 Antibody AF1387a
    AF1387a (0.5 µg/ml) staining of paraffin embedded Human Pancreas. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UPT5
Other Accession NP_056034, 23265
Reactivity Human
Predicted Mouse, Rat, Pig, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 83382 Da
Additional Information
Gene ID 23265
Other Names Exocyst complex component 7, Exocyst complex component Exo70, EXOC7, EXO70, KIAA1067
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-EXOC7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EXOC7
Synonyms EXO70, KIAA1067
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion (By similarity).
Cellular Location Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein Note=Translocates, as a preformed complex with SEC6 and SEC8, to the plasma membrane in response to insulin through the activation of ARHQ.
Research Areas
Citations (0)

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EXOC7 is a component of the exocyst, which is an evolutionarily conserved octameric protein complex essential for exocytosis. The exocyst targets secretory vesicles at specific domains of the plasma membrane for cell surface expansion and protein secretion (Zuo et al., 2006 [PubMed 17086175]).


Novel interaction partners of Bardet-Biedl syndrome proteins. Oeffner F, et al. Cell Motil Cytoskeleton, 2008 Feb. PMID 18000879.
Exo70 interacts with the Arp2/3 complex and regulates cell migration. Zuo X, et al. Nat Cell Biol, 2006 Dec. PMID 17086175.
A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Beausoleil SA, et al. Nat Biotechnol, 2006 Oct. PMID 16964243.
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.
Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.

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$ 325.00
Cat# AF1387a
(40 western blots)
Availability: 7-10 days
Bulk Size
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