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FADS1 AntibodyPeptide-affinity purified goat antibody

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AF1396a 0.1mg 400 ul 7-10 days $ 325.00 Add to cart
  • Specification
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  • Protocols
  • Backgrounds

FADS1 Antibody - Product info

Other AccessionNP_037534
ReactivityHuman
Concentration100ug/200ul
IsotypeIgG

FADS1 Antibody - Additional info

Other Names
FADS1; fatty acid desaturase 1 ; D5D; FADS6; FADSD5; FLJ38956; FLJ90273; LLCDL1; TU12 ; delta-5 desaturase; delta-5 fatty acid desaturase; linoleoyl-CoA desaturase (delta-6-desaturase)-like 1
Format
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
FADS1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

FADS1 Antibody - Application data

  • AF1396a (0.3 µg/ml) staining of Human Lung lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

FADS1 Antibody - Related products

RI11908: FADS1 predesign siRNA

AT1989a: FADS1 Antibody (monoclonal) (M04)

AF1396a: FADS1 Antibody

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.

REFERENCES

Genetic variation of the FADS1 FADS2 gene cluster and n-6 PUFA composition in erythrocyte membranes in the European Prospective Investigation into Cancer and Nutrition-Potsdam study. Zietemann V, et al. Br J Nutr, 2010 Aug 9. PMID 20691134. Genome-wide association analysis identifies multiple loci related to resting heart rate. Eijgelsheim M, et al. Hum Mol Genet, 2010 Oct 1. PMID 20639392. Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086. Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. Fontaine-Bisson B, et al. Diabetologia, 2010 Oct. PMID 20571754. FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population. Mathias RA, et al. J Lipid Res, 2010 Sep. PMID 20562440.