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Goat Anti-FOXC2 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-FOXC2 Antibody AF1428a
    HEK293 lysate (10ug protein in RIPA buffer) over expressing Human FOXC2 with DYKDDDDK tag probed with AF1428a (0.1ug/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/1000) in lane C. Mock-transfected HEK293 probed with AF1428a (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence.
  • IHC - Goat Anti-FOXC2 Antibody AF1428a
    Antibody (2µg/ml) staining of paraffin embedded Human Breast cancer. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99958
Other Accession NP_005242.1, 2303, 14234 (mouse)
Reactivity Human
Predicted Mouse, Rat, Cow, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 53719 Da
Additional Information
Gene ID 2303
Other Names Forkhead box protein C2, Forkhead-related protein FKHL14, Mesenchyme fork head protein 1, MFH-1 protein, Transcription factor FKH-14, FOXC2, FKHL14, MFH1
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-FOXC2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXC2
Synonyms FKHL14, MFH1
Function Transcriptional activator. Might be involved in the formation of special mesenchymal tissues.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089, ECO:0000269|PubMed:23878394}
Research Areas
Citations (0)

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This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.


Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.
A novel missense mutation and two microrearrangements in the FOXC2 gene of three families with lymphedema-distichiasis syndrome. Fauret AL, et al. Lymphology, 2010 Mar. PMID 20552815.
Gestational diabetes mellitus shares polymorphisms of genes associated with insulin resistance and type 2 diabetes in the Greek population. Pappa KI, et al. Gynecol Endocrinol, 2010 Jun 14. PMID 20540670.
A case of lymphedema-distichiasis syndrome carrying a new de novo frameshift FOXC2 mutation. Fabretto A, et al. Ophthalmic Genet, 2010 Jun. PMID 20450314.
Lymphedema-distichiasis syndrome without FOXC2 mutation: evidence for chromosome 16 duplication upstream of FOXC2. Witte MH, et al. Lymphology, 2009 Dec. PMID 20218083.

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$ 325.00
Cat# AF1428a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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