Goat Anti-FOXC2 Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q99958 |
Other Accession | NP_005242.1, 2303, 14234 (mouse) |
Reactivity | Human |
Predicted | Mouse, Rat, Cow, Dog |
Host | Goat |
Clonality | Polyclonal |
Concentration | 100ug/200ul |
Isotype | IgG |
Calculated MW | 53719 Da |
Gene ID | 2303 |
---|---|
Other Names | Forkhead box protein C2, Forkhead-related protein FKHL14, Mesenchyme fork head protein 1, MFH-1 protein, Transcription factor FKH-14, FOXC2, FKHL14, MFH1 |
Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-FOXC2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FOXC2 |
---|---|
Synonyms | FKHL14, MFH1 |
Function | Transcriptional activator. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089, ECO:0000269|PubMed:23878394, ECO:0000269|PubMed:28179430} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.
References
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.
A novel missense mutation and two microrearrangements in the FOXC2 gene of three families with lymphedema-distichiasis syndrome. Fauret AL, et al. Lymphology, 2010 Mar. PMID 20552815.
Gestational diabetes mellitus shares polymorphisms of genes associated with insulin resistance and type 2 diabetes in the Greek population. Pappa KI, et al. Gynecol Endocrinol, 2010 Jun 14. PMID 20540670.
A case of lymphedema-distichiasis syndrome carrying a new de novo frameshift FOXC2 mutation. Fabretto A, et al. Ophthalmic Genet, 2010 Jun. PMID 20450314.
Lymphedema-distichiasis syndrome without FOXC2 mutation: evidence for chromosome 16 duplication upstream of FOXC2. Witte MH, et al. Lymphology, 2009 Dec. PMID 20218083.
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