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Goat Anti-FRA1 / FOSL1 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-FRA1 / FOSL1 Antibody AF1441a
    AF1441a (1 µg/ml) staining of Human Bone Marrow lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P15407
Other Accession NP_005429, 8061, 14283 (mouse), 25445 (rat)
Reactivity Human
Predicted Mouse, Rat, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 29413 Da
Additional Information
Gene ID 8061
Other Names Fos-related antigen 1, FRA-1, FOSL1, FRA1
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-FRA1 / FOSL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOSL1
Synonyms FRA1
Cellular Location Nucleus.
Research Areas
Citations (0)

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The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.


AP-1 (Fra-1/c-Jun)-mediated induction of expression of matrix metalloproteinase-2 is required for 15S-hydroxyeicosatetraenoic acid-induced angiogenesis. Singh NK, et al. J Biol Chem, 2010 May 28. PMID 20353950.
[Expression of the FOSL1 gene in psoriasis and atherosclerosis] Sobolev VV, et al. Genetika, 2010 Jan. PMID 20198886.
Human papillomavirus type 8 E2 protein unravels JunB/Fra-1 as an activator of the beta4-integrin gene in human keratinocytes. Oldak M, et al. J Virol, 2010 Feb. PMID 19923172.
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.
Genetical genomic determinants of alcohol consumption in rats and humans. Tabakoff B, et al. BMC Biol, 2009 Oct 27. PMID 19874574.

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$ 325.00
Cat# AF1441a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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