Goat Anti-GCIP-interacting protein p29 Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | O95926 |
Other Accession | NP_997053, 25949, 68592 (mouse), 170933 (rat) |
Reactivity | Human, Mouse |
Predicted | Rat, Dog, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 100ug/200ul |
Isotype | IgG |
Calculated MW | 28722 Da |
Gene ID | 25949 |
---|---|
Other Names | Pre-mRNA-splicing factor SYF2, CCNDBP1-interactor, p29, SYF2, CBPIN, GCIPIP |
Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-GCIP-interacting protein p29 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SYF2 |
---|---|
Synonyms | CBPIN, GCIPIP |
Function | Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28076346). |
Cellular Location | Nucleus |
Tissue Location | Abundantly expressed in the heart, skeletal muscle and kidney. Expressed at lower level other tissues |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a nuclear protein that interacts with cyclin D-type binding-protein 1, which is thought to be a cell cycle regulator at the G1/S transition. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
References
Silencing of p29 affects DNA damage responses with UV irradiation. Chu PC, et al. Cancer Res, 2006 Sep 1. PMID 16951160.
The DNA sequence and biological annotation of human chromosome 1. Gregory SG, et al. Nature, 2006 May 18. PMID 16710414.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. Jurica MS, et al. RNA, 2002 Apr. PMID 11991638.
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