|Application ||WB, E|
|Other Accession||NP_005426, 7984|
|Calculated MW||176799 Da|
|Other Names||Rho guanine nucleotide exchange factor 5, Ephexin-3, Guanine nucleotide regulatory protein TIM, Oncogene TIM, Transforming immortalized mammary oncogene, p60 TIM, ARHGEF5, TIM|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-GEF5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Mainly expressed in kidney, liver, pancreas, lung and placenta|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.
Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5. Wang Z, et al. J Biol Chem, 2009 Oct 16. PMID 19713215.
Disturbance of circadian gene expression in hepatocellular carcinoma. Lin YM, et al. Mol Carcinog, 2008 Dec. PMID 18444243.
Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. Zhang Y, et al. Mol Cell Proteomics, 2005 Sep. PMID 15951569.
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