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Goat Anti-GJB2 / Connexin 26 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-GJB2 / Connexin 26 Antibody AF1482a
    AF1482a (0.01 µg/ml) staining of Mouse Brain lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P29033
Other Accession NP_003995, 2706, 14619 (mouse), 394266 (rat)
Reactivity Mouse
Predicted Human, Rat
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 26215 Da
Additional Information
Gene ID 2706
Other Names Gap junction beta-2 protein, Connexin-26, Cx26, GJB2
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-GJB2 / Connexin 26 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GJB2
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
Research Areas
Citations (0)

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This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.


Carrier frequency of GJB2 gene mutations c.35delG, c.235delC and c.167delT among the populations of Eurasia. Dzhemileva LU, et al. J Hum Genet, 2010 Aug 26. PMID 20739944.
Genetic causes of nonsyndromic hearing loss in Iran in comparison with other populations. Mahdieh N, et al. J Hum Genet, 2010 Aug 26. PMID 20739942.
Prevalence of c.35delG and p.M34T mutations in the GJB2 gene in Estonia. Teek R, et al. Int J Pediatr Otorhinolaryngol, 2010 Sep. PMID 20708129.
A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). Romero R, et al. Am J Obstet Gynecol, 2010 Jul 29. PMID 20673868.
Genotyping with a 198 mutation arrayed primer extension array for hereditary hearing loss: assessment of its diagnostic value for medical practice. Rodriguez-Paris J, et al. PLoS One, 2010 Jul 26. PMID 20668687.

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$ 325.00
Cat# AF1482a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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