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Goat Anti-GPR3 Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-GPR3 Antibody AF1494a
    AF1494a (0.3 µg/ml) staining of Human Brain (Frontal Cortex) lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P46089
Other Accession NP_005272, 2827, 14748 (mouse), 266769 (rat)
Reactivity Human
Predicted Mouse, Rat, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 35010 Da
Additional Information
Gene ID 2827
Other Names G-protein coupled receptor 3, ACCA orphan receptor, GPR3, ACCA
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-GPR3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPR3
Synonyms ACCA
Function Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Has a potential role in modulating a number of brain functions, including behavioral responses to stress (By similarity), amyloid-beta peptide generation in neurons and neurite outgrowth (By similarity). Maintains also meiotic arrest in oocytes (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed predominantly in the central nervous system, and at low levels in the lung, kidney, testis, ovary and eye. Highly expressed in regions of the brain implicated in the Alzheimer disease
Research Areas
Citations (0)

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References

GPR3 may not be a potential candidate gene for premature ovarian failure. Zhou S, et al. Reprod Biomed Online, 2010 Jan. PMID 20158988.
Oocyte-specific G-protein-coupled receptor 3 (GPR3): no perturbations found in 82 women with premature ovarian failure (first report). Kovanci E, et al. Fertil Steril, 2008 Oct. PMID 17953967.
The DNA sequence and biological annotation of human chromosome 1. Gregory SG, et al. Nature, 2006 May 18. PMID 16710414.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
Fluid shear stress differentially regulates gpr3, gpr6, and gpr12 expression in human umbilical vein endothelial cells. Uhlenbrock K, et al. Cell Physiol Biochem, 2003. PMID 12649592.

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$ 325.00
Cat# AF1494a
Size:
Quantity:
(40 western blots)
Availability: 7-10 days
Bulk Size
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