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Goat Anti-GPX7 Antibody

Peptide-affinity purified goat antibody

     
  • EIA - Goat Anti-GPX7 Antibody AF1502a
    EB7319 (5ug/ml) as the reporter with EB002012 as the capture rabbit antibody (5ug/ml).
    detail
  • WB - Goat Anti-GPX7 Antibody AF1502a
    AF1502a (0.3µg/ml) staining of Human Prostate lysate (35µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, Pep-ELISA
Primary Accession Q96SL4
Other Accession NP_056511.2, 2882, 67305 (mouse), 298376 (rat)
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 20996 Da
Additional Information
Gene ID 2882
Other Names Glutathione peroxidase 7, GPx-7, GSHPx-7, 1.11.1.9, CL683, GPX7, GPX6
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-GPX7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPX7
Synonyms GPX6
Function It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxygen species (ROS) and protects against oxidative DNA damage and double-strand breaks.
Cellular Location Secreted.
Tissue Location Expressed in esophageal epithelial cells; expression is up-regulated after exposure to acidic bile acids
Research Areas
Citations (0)
citation

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References

Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy. Moyer AM, et al. Cancer Epidemiol Biomarkers Prev, 2010 Mar. PMID 20200426.
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Lim J, et al. Cell, 2006 May 19. PMID 16713569.
The DNA sequence and biological annotation of human chromosome 1. Gregory SG, et al. Nature, 2006 May 18. PMID 16710414.

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$ 341.00
Cat# AF1502a
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