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Goat Anti-GRAP2 / GRID / Grf40 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-GRAP2 / GRID / Grf40 Antibody AF1506a
    HEK293 overexpressing GRAP2 (RC206546) and probed with AF1506a (mock transfection in first lane), tested by Origene.
  • WB - Goat Anti-GRAP2 / GRID / Grf40 Antibody AF1506a
    HEK293 overexpressing GRAP2 (RC206546) and probed with Antibody (mock transfection in first lane), tested by Origene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75791
Other Accession NP_004801, 9402, 17444 (mouse)
Reactivity Human
Predicted Mouse, Rat, Pig, Cow, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 37909 Da
Additional Information
Gene ID 9402
Other Names GRB2-related adapter protein 2, Adapter protein GRID, GRB-2-like protein, GRB2L, GRBLG, GRBX, Grf40 adapter protein, Grf-40, Growth factor receptor-binding protein, Hematopoietic cell-associated adapter protein GrpL, P38, Protein GADS, SH3-SH2-SH3 adapter Mona, GRAP2, GADS, GRB2L, GRID
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-GRAP2 / GRID / Grf40 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRAP2
Synonyms GADS, GRB2L, GRID
Function Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
Cellular Location Nucleus. Cytoplasm. Endosome
Research Areas
Citations (0)

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This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.


Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.
The Bcr-Abl kinase regulates the actin cytoskeleton via a GADS/Slp-76/Nck1 adaptor protein pathway. Preisinger C, et al. Cell Signal, 2010 May. PMID 20079431.
Secreted protein acidic and rich in cysteine (SPARC) gene polymorphism association with hepatocellular carcinoma in Italian patients. Segat L, et al. J Gastroenterol Hepatol, 2009 Dec. PMID 19817957.
Expression of the Grb2-related RET adapter protein Grap-2 in human medullary thyroid carcinoma. Ludwig L, et al. Cancer Lett, 2009 Mar 18. PMID 19027225.

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$ 325.00
Cat# AF1506a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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