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Goat Anti-IDS Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-IDS Antibody AF1553a
    AF1553a (0.1 µg/ml) staining of Human Liver lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • IHC - Goat Anti-IDS Antibody AF1553a
    AF1553a (3.8 µg/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P22304
Other Accession NP_000193, 3423
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 61873 Da
Additional Information
Gene ID 3423
Other Names Iduronate 2-sulfatase,, Alpha-L-iduronate sulfate sulfatase, Idursulfase, Iduronate 2-sulfatase 42 kDa chain, Iduronate 2-sulfatase 14 kDa chain, IDS, SIDS
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-IDS Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IDS
Synonyms SIDS
Function Required for the lysosomal degradation of heparan sulfate and dermatan sulfate.
Cellular Location Lysosome.
Tissue Location Liver, kidney, lung, and placenta.
Research Areas
Citations (0)

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Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
Common genetic variation and performance on standardized cognitive tests. Cirulli ET, et al. Eur J Hum Genet, 2010 Jul. PMID 20125193.
Enigmatic in vivo iduronate-2-sulfatase (IDS) mutant transcript correction to wild-type in Hunter syndrome. Lualdi S, et al. Hum Mutat, 2010 Apr. PMID 20104590.
[Identification of a novel mutation of IDS gene from a Chinese pedigree with MPS II] GUO YB, et al. Yi Chuan, 2009 Nov. PMID 19933090.
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.

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$ 325.00
Cat# AF1553a
(40 western blots)
Availability: 7-10 days
Bulk Size
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