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Goat Anti-IRF5 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-IRF5 Antibody AF1571a
    Antibody staining (1µg/ml) of A549 (A), Human Spleen (B) and Peripheral Blood Lymphocytes (C) lysates (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence
  • WB - Goat Anti-IRF5 Antibody AF1571a
    Antibody staining (1µg/ml) of A549 (A), Human Spleen (B) and Peripheral Blood Lymphocytes (C) lysates (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13568
Other Accession NP_001092099, 3663
Reactivity Human
Predicted Mouse, Rat, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 56044 Da
Additional Information
Gene ID 3663
Other Names Interferon regulatory factor 5, IRF-5, IRF5
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-IRF5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IRF5
Function Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling.
Cellular Location Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm
Research Areas
Citations (0)

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This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.


Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis. Liu X, et al. Nat Genet, 2010 Aug. PMID 20639880.
Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis. Hirschfield GM, et al. Nat Genet, 2010 Aug. PMID 20639879.
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
Genetic Differences between Five European Populations. Moskvina V, et al. Hum Hered, 2010 Jul 8. PMID 20616560.
Dengue hemorrhagic fever is associated with polymorphisms in JAK1. Silva LK, et al. Eur J Hum Genet, 2010 Jun 30. PMID 20588308.

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$ 325.00
Cat# AF1571a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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