|Application ||WB, E|
|Other Accession||NP_002220, 3726, 16477 (mouse), 24517 (rat)|
|Predicted||Mouse, Rat, Dog, Cow|
|Calculated MW||35879 Da|
|Other Names||Transcription factor jun-B, JUNB|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-JUNB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Over-expression of JunB inhibits mitochondrial stress and cytotoxicity in human lymphoma cells exposed to chronic oxidative stress. Son YO, et al. BMB Rep, 2010 Jan. PMID 20132737.
[Expression and functional analysis of transcriptional factor JunB in hepatic cancer cells] Wang L, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 2010 Jan. PMID 20056077.
DNA methylation does not regulate JUNB expression in CML: comment on Downregulation of JUNB mRNA expression in advanced phase chronic myelogenous leukemia by Hoshino et al. [Leuk. Res. 33 (2009) 1361-1366]. Strathdee G, et al. Leuk Res, 2010 May. PMID 20006998.
Human papillomavirus type 8 E2 protein unravels JunB/Fra-1 as an activator of the beta4-integrin gene in human keratinocytes. Oldak M, et al. J Virol, 2010 Feb. PMID 19923172.
Expression and clinical significance of p53, JunB and KAI1/CD82 in human hepatocellular carcinoma. Guo C, et al. Hepatobiliary Pancreat Dis Int, 2009 Aug. PMID 19666408.
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