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Goat Anti-JUNB Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-JUNB Antibody AF1578a
    AF1578a (0.3 µg/ml) staining of Human Breast Cancer lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P17275
Other Accession NP_002220, 3726, 16477 (mouse), 24517 (rat)
Reactivity Human
Predicted Mouse, Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 35879 Da
Additional Information
Gene ID 3726
Other Names Transcription factor jun-B, JUNB
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-JUNB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name JUNB
Function Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[GC]TCA-3'. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to an AP-1 consensus sequence and its transcriptional activity (By similarity).
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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References

Over-expression of JunB inhibits mitochondrial stress and cytotoxicity in human lymphoma cells exposed to chronic oxidative stress. Son YO, et al. BMB Rep, 2010 Jan. PMID 20132737.
[Expression and functional analysis of transcriptional factor JunB in hepatic cancer cells] Wang L, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 2010 Jan. PMID 20056077.
DNA methylation does not regulate JUNB expression in CML: comment on Downregulation of JUNB mRNA expression in advanced phase chronic myelogenous leukemia by Hoshino et al. [Leuk. Res. 33 (2009) 1361-1366]. Strathdee G, et al. Leuk Res, 2010 May. PMID 20006998.
Human papillomavirus type 8 E2 protein unravels JunB/Fra-1 as an activator of the beta4-integrin gene in human keratinocytes. Oldak M, et al. J Virol, 2010 Feb. PMID 19923172.
Expression and clinical significance of p53, JunB and KAI1/CD82 in human hepatocellular carcinoma. Guo C, et al. Hepatobiliary Pancreat Dis Int, 2009 Aug. PMID 19666408.

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$ 341.00
Cat# AF1578a
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