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Goat Anti-Kinesin 1 / UKHC Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-Kinesin 1 / UKHC Antibody AF1590a
    AF1590a (0.5 µg/ml) staining of lysate of cell line Jurkat (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • IHC - Goat Anti-Kinesin 1 / UKHC Antibody AF1590a
    AF1590a (1 µg/ml) staining of paraffin embedded Human Kidney. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. Please note this data was obtained with a previous batch.
  • IHC - Goat Anti-Kinesin 1 / UKHC Antibody AF1590a
    AF1590a (2.5 µg/ml) staining of paraffin embedded Human Uterus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Please note this data was obtained with a previous batch.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P33176
Other Accession NP_004512, 3799
Reactivity Human, Dog
Predicted Mouse, Rat, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 109685 Da
Additional Information
Gene ID 3799
Other Names Kinesin-1 heavy chain, Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain, UKHC, KIF5B, KNS, KNS1
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Kinesin 1 / UKHC Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KIF5B
Synonyms KNS, KNS1
Function Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.
Cellular Location Cytoplasm, cytoskeleton. Note=Uniformly distributed between soma and neurites in hippocampal neurons.
Research Areas
Citations (0)

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Microtubule-associated protein-like binding of the kinesin-1 tail to microtubules. Seeger MA, et al. J Biol Chem, 2010 Mar 12. PMID 20071331.
Kinesin-1 plays a role in transport of SNAP-25 to the plasma membrane. Morton AM, et al. Biochem Biophys Res Commun, 2010 Jan 1. PMID 19913510.
Role of kinesin light chain-2 of kinesin-1 in the traffic of Na,K-ATPase-containing vesicles in alveolar epithelial cells. Trejo HE, et al. FASEB J, 2010 Feb. PMID 19773350.
Kif5b is an essential forward trafficking motor for the Kv1.5 cardiac potassium channel. Zadeh AD, et al. J Physiol, 2009 Oct 1. PMID 19675065.
Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.

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$ 325.00
Cat# AF1590a
(40 western blots)
Availability: 7-10 days
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