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Goat Anti-LDHC (aa 221 - 233) Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, E |
|---|---|
| Primary Accession | P07864 |
| Other Accession | NP_059144, 3948, 16833 (mouse) |
| Reactivity | Mouse |
| Predicted | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5mg/ml |
| Isotype | IgG |
| Calculated MW | 36311 Da |
| Gene ID | 3948 |
|---|---|
| Other Names | L-lactate dehydrogenase C chain, LDH-C, 1.1.1.27, Cancer/testis antigen 32, CT32, LDH testis subunit, LDH-X, LDHC, LDH3, LDHX |
| Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-LDHC (aa 221 - 233) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LDHC |
|---|---|
| Synonyms | LDH3, LDHX |
| Function | Possible role in sperm motility. |
| Cellular Location | Cytoplasm. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHC is testis-specific and belongs to the lactate dehydrogenase family. Two transcript variants have been detected which differ in the 5' untranslated region.
References
Homo sapiens lactate dehydrogenase c (Ldhc) gene expression in cancer cells is regulated by transcription factor Sp1, CREB, and CpG island methylation. Tang H, et al. J Androl, 2009 Mar-Apr. PMID 18930904.
Construction of sperm-specific lactate dehydrogenase DNA vaccine and experimental study of its immunocontraceptive effect on mice. Chen Y, et al. Sci China C Life Sci, 2008 Apr. PMID 18368308.
Elevated level of serum LDH2 and LDH3 in sputum three positive TB patients of Sahariya tribe: a preliminary study. Sharma PR, et al. Clin Biochem, 2007 Dec. PMID 17935709.
Increased serum lactate dehydrogenase isoenzymes in Ph-negative chronic myeloproliferative diseases: a metabolic adaptation? Mazzotta S, et al. Hematology, 2006 Aug. PMID 17178662.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
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