|Application ||WB, E, EIA|
|Other Accession||NP_000889, 4129, 109731 (mouse)|
|Predicted||Mouse, Rat, Pig, Dog, Cow|
|Calculated MW||58763 Da|
|Other Names||Amine oxidase [flavin-containing] B, 126.96.36.199, Monoamine oxidase type B, MAO-B, MAOB|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-MAOB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.|
|Cellular Location||Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine.
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
Smoking, genes encoding dopamine pathway and risk for Parkinson's disease. Gu Z, et al. Neurosci Lett, 2010 Sep 20. PMID 20603187.
Association study between antipsychotic-induced restless legs syndrome and polymorphisms of monoamine oxidase genes in schizophrenia. Kang SG, et al. Hum Psychopharmacol, 2010 Jul. PMID 20589923.
A case-control study of Parkinson's disease and tobacco use: gene-tobacco interactions. De Palma G, et al. Mov Disord, 2010 May 15. PMID 20461808.
Aggressive behavior, related conduct problems, and variation in genes affecting dopamine turnover. Grigorenko EL, et al. Aggress Behav, 2010 May. PMID 20127808.
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