|Application ||WB, E|
|Other Accession||NP_001015054, 4350|
|Calculated MW||32869 Da|
|Other Names||DNA-3-methyladenine glycosylase, 220.127.116.11, 3-alkyladenine DNA glycosylase, 3-methyladenine DNA glycosidase, ADPG, N-methylpurine-DNA glycosylase, MPG, AAG, ANPG, MID1|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-MPG Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||AAG, ANPG, MID1|
|Function||Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.|
|Cellular Location||Cytoplasm. Mitochondrion matrix, mitochondrion nucleoid. Nucleus|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Polymorphisms in the base excision repair pathway and graft-versus-host disease. Arora M, et al. Leukemia, 2010 Aug. PMID 20574454.
Variation within DNA repair pathway genes and risk of multiple sclerosis. Briggs FB, et al. Am J Epidemiol, 2010 Jul 15. PMID 20522537.
Frameshift mutagenesis and microsatellite instability induced by human alkyladenine DNA glycosylase. Klapacz J, et al. Mol Cell, 2010 Mar 26. PMID 20347426.
Association between genetic variants in the base excision repair pathway and outcomes after hematopoietic cell transplantations. Thyagarajan B, et al. Biol Blood Marrow Transplant, 2010 Aug. PMID 20226869.
Hopping enables a DNA repair glycosylase to search both strands and bypass a bound protein. Hedglin M, et al. ACS Chem Biol, 2010 Apr 16. PMID 20201599.
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