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Goat Anti-MPS1 / RPS27 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-MPS1 / RPS27 Antibody AF1681a
    AF1681a (0.03 µg/ml) staining of Jurkat lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P42677
Other Accession NP_001021, 6232, 57294 (mouse), 94266 (rat)
Reactivity Human
Predicted Mouse, Rat
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 9461 Da
Additional Information
Gene ID 6232
Other Names 40S ribosomal protein S27, Metallopan-stimulin 1, MPS-1, RPS27, MPS1
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-MPS1 / RPS27 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RPS27
Synonyms MPS1
Tissue Location Expressed in a wide variety of actively proliferating cells and tumor tissues
Research Areas
Citations (0)

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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.


Synchronised phosphorylation of BNIP3, Bcl-2 and Bcl-xL in response to microtubule-active drugs is JNK-independent and requires a mitotic kinase. Mellor HR, et al. Biochem Pharmacol, 2010 Jun 1. PMID 20100468.
Extraribosomal function of metallopanstimulin-1: reducing paxillin in head and neck squamous cell carcinoma and inhibiting tumor growth. Dai Y, et al. Int J Cancer, 2010 Feb 1. PMID 19642098.
Phosphoregulation of human Mps1 kinase. Tyler RK, et al. Biochem J, 2009 Jan 1. PMID 18680479.
Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment. Jelluma N, et al. Cell, 2008 Jan 25. PMID 18243099.
PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores. Montembault E, et al. J Cell Biol, 2007 Nov 19. PMID 17998396.

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$ 325.00
Cat# AF1681a
(40 western blots)
Availability: 7-10 days
Bulk Size
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