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Goat Anti-MRPL3 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-MRPL3 Antibody AF1685a
    AF1685a staining (1 µg/ml) of HepG2 cell lysate (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09001
Other Accession NP_009139, 11222
Reactivity Human
Predicted Pig, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 38633 Da
Additional Information
Gene ID 11222
Other Names 39S ribosomal protein L3, mitochondrial, L3mt, MRP-L3, MRPL3, MRL3, RPML3
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-MRPL3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MRPL3
Synonyms MRL3, RPML3
Cellular Location Mitochondrion.
Research Areas
Citations (0)

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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q.


The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. Zhang Z, et al. Genomics, 2003 May. PMID 12706105.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. Kenmochi N, et al. Genomics, 2001 Sep. PMID 11543634.
Cloning and characterization of a human ribosomal protein gene with enhanced expression in fetal and neoplastic cells. Ou JH, et al. Nucleic Acids Res, 1987 Nov 11. PMID 2891103.

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$ 325.00
Cat# AF1685a
(40 western blots)
Availability: 7-10 days
Bulk Size
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