|Application ||WB, E|
|Other Accession||NP_000521, 4359|
|Predicted||Human, Mouse, Dog|
|Calculated MW||27555 Da|
|Other Names||Myelin protein P0, Myelin peripheral protein, MPP, Myelin protein zero, MPZ|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Myelin Protein zero Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Found only in peripheral nervous system Schwann cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies.
Charcot-Marie-Tooth disease with intermediate conduction velocities caused by a novel mutation in the MPZ gene. Banchs I, et al. Muscle Nerve, 2010 Aug. PMID 20544920.
Charcot-Marie-Tooth disease due to novel myelin protein zero mutation presenting as late-onset remitting sensory neuropathy. Simpson BS, et al. J Clin Neuromuscul Dis, 2010 Jun. PMID 20516806.
Asymmetric phenotype associated with rare myelin protein zero mutation. Souayah N, et al. J Clin Neuromuscul Dis, 2010 Mar. PMID 20215982.
Laryngeal neuropathy of Charcot-Marie-Tooth disease: further observations and novel mutations associated with vocal fold paresis. Benson B, et al. Laryngoscope, 2010 Feb. PMID 19950375.
[Predominant parasympathetic involvement in a patient with Charcot-Marie-Tooth disease caused by the MPZ Thr124Met mutation] Nakamura N, et al. Rinsho Shinkeigaku, 2009 Sep. PMID 19928689.
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