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Goat Anti-Myelin Protein zero Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-Myelin Protein zero Antibody AF1702a
    AF1702a (0.1 µg/ml) staining of Rat Spinal Cord lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P25189
Other Accession NP_000521, 4359
Reactivity Rat
Predicted Human, Mouse, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 27555 Da
Additional Information
Gene ID 4359
Other Names Myelin protein P0, Myelin peripheral protein, MPP, Myelin protein zero, MPZ
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Myelin Protein zero Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MPZ
Function Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Found only in peripheral nervous system Schwann cells
Research Areas
Citations (0)

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This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies.


Charcot-Marie-Tooth disease with intermediate conduction velocities caused by a novel mutation in the MPZ gene. Banchs I, et al. Muscle Nerve, 2010 Aug. PMID 20544920.
Charcot-Marie-Tooth disease due to novel myelin protein zero mutation presenting as late-onset remitting sensory neuropathy. Simpson BS, et al. J Clin Neuromuscul Dis, 2010 Jun. PMID 20516806.
Asymmetric phenotype associated with rare myelin protein zero mutation. Souayah N, et al. J Clin Neuromuscul Dis, 2010 Mar. PMID 20215982.
Laryngeal neuropathy of Charcot-Marie-Tooth disease: further observations and novel mutations associated with vocal fold paresis. Benson B, et al. Laryngoscope, 2010 Feb. PMID 19950375.
[Predominant parasympathetic involvement in a patient with Charcot-Marie-Tooth disease caused by the MPZ Thr124Met mutation] Nakamura N, et al. Rinsho Shinkeigaku, 2009 Sep. PMID 19928689.

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$ 325.00
Cat# AF1702a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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