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Goat Anti-Myosin IXB Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-Myosin IXB Antibody AF1704a
    AF1704a (2 µg/ml) staining of Human Liver lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13459
Other Accession NP_004136, 4650
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 243401 Da
Additional Information
Gene ID 4650
Other Names Unconventional myosin-IXb, Unconventional myosin-9b, MYO9B, MYR5
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Myosin IXB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MYO9B
Synonyms MYR5
Function Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. May be involved in the remodeling of the actin cytoskeleton. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions. Also acts as a GTPase activating protein on Rho.
Cellular Location Cytoplasm, cell cortex. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Note=In undifferentiated cells colocalizes with F-actin in the cell periphery while in differentiated cells its localization is cytoplasmic with the highest levels in the perinuclear region
Tissue Location Expressed predominantly in peripheral blood leukocytes and at lower levels, in thymus, spleen, testis, prostate, ovary, brain, small intestine and lung
Research Areas
Citations (0)

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This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.


Association analysis of myosin IXB and type 1 diabetes. Persengiev S, et al. Hum Immunol, 2010 Jun. PMID 20303373.
Intestinal barrier gene variants may not explain the increased levels of antigliadin antibodies, suggesting other mechanisms than altered permeability. Wolters VM, et al. Hum Immunol, 2010 Apr. PMID 20096742.
Mutation of ARHGAP9 in patients with coronary spastic angina. Takefuji M, et al. J Hum Genet, 2010 Jan. PMID 19911011.
Association between genetic variants in myosin IXB and Crohn's disease. Cooney R, et al. Inflamm Bowel Dis, 2009 Jul. PMID 19235913.
MYO9B polymorphisms in multiple sclerosis. Kemppinen A, et al. Eur J Hum Genet, 2009 Jun. PMID 19142207.

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$ 325.00
Cat# AF1704a
(40 western blots)
Availability: 7-10 days
Bulk Size
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