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Goat Anti-MYRIP / SLAC2C Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-MYRIP / SLAC2C Antibody AF1705a
    AF1705a (0.3 µg/ml) staining of Human Amygdala lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NFW9
Other Accession NP_056275, 25924
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 95706 Da
Additional Information
Gene ID 25924
Other Names Rab effector MyRIP, Exophilin-8, Myosin-VIIa- and Rab-interacting protein, Synaptotagmin-like protein lacking C2 domains C, SlaC2-c, Slp homolog lacking C2 domains c, MYRIP, SLAC2C
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-MYRIP / SLAC2C Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SLAC2C
Function Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity).
Cellular Location Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, secretory vesicle. Note=In presynaptic and postsynaptic areas in photoreceptor cells and in the basal microvilli of retinal pigment epithelium cells. Associated with melanosomes. Colocalizes with actin filaments (By similarity).
Tissue Location Detected in brain, skin, heart, adrenal medulla, pancreas, intestine, liver, kidney, muscle and testis
Research Areas
Citations (0)

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Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells. Nightingale TD, et al. Blood, 2009 May 14. PMID 19270261.
Intramanchette transport during primate spermiogenesis: expression of dynein, myosin Va, motor recruiter myosin Va, VIIa-Rab27a/b interacting protein, and Rab27b in the manchette during human and monkey spermiogenesis. Hayasaka S, et al. Asian J Androl, 2008 Jul. PMID 18478159.
Genome-wide association of sleep and circadian phenotypes. Gottlieb DJ, et al. BMC Med Genet, 2007 Sep 19. PMID 17903308.
MyRIP anchors protein kinase A to the exocyst complex. Goehring AS, et al. J Biol Chem, 2007 Nov 9. PMID 17827149.

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$ 325.00
Cat# AF1705a
(40 western blots)
Availability: 7-10 days
Bulk Size
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