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Goat Anti-Neurotrophin 5 / NT4 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-Neurotrophin 5 / NT4 Antibody AF1727a
    AF1727a (0.1 µg/ml) staining of Human Cerebellum lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P34130
Other Accession NP_006170, 4909
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 22427 Da
Additional Information
Gene ID 4909
Other Names Neurotrophin-4, NT-4, Neurotrophin-5, NT-5, Neutrophic factor 4, NTF4, NTF5
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Neurotrophin 5 / NT4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NTF4
Synonyms NTF5
Function Target-derived survival factor for peripheral sensory sympathetic neurons.
Cellular Location Secreted.
Tissue Location Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues
Research Areas
Citations (0)

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This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.


Identification of a novel mutation in the NTF4 gene that causes primary open-angle glaucoma in a Chinese population. Vithana EN, et al. Mol Vis, 2010 Aug 15. PMID 20806036.
Variations in NTF4, VAV2 and VAV3 Genes Are Not Involved With Primary Open Angle and Primary Angle Closure Glaucomas in an Indian Population. Rao KN, et al. Invest Ophthalmol Vis Sci, 2010 May 12. PMID 20463313.
Role of the neurotrophin network in eating disorders' subphenotypes: body mass index and age at onset of the disease. Gratac貌s M, et al. J Psychiatr Res, 2010 Oct. PMID 20219210.
No evidence of association of heterozygous NTF4 mutations in patients with primary open-angle glaucoma. Liu Y, et al. Am J Hum Genet, 2010 Mar 12. PMID 20215012.
Differential expression and regulation by activin of the neurotrophins BDNF and NT4 during human and mouse ovarian development. Childs AJ, et al. Dev Dyn, 2010 Apr. PMID 20175187.

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$ 325.00
Cat# AF1727a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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