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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat Anti-NIPP1 / PPP1R8 Antibody
Goat Anti-NIPP1 / PPP1R8 Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
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Application 
| WB, IHC, E |
|---|---|
| Primary Accession | Q12972 |
| Other Accession | NP_612568, 5511, 100336 (mouse) |
| Reactivity | Human |
| Predicted | Mouse, Rat, Dog, Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 100ug/200ul |
| Isotype | IgG |
| Calculated MW | 38479 Da |
| Gene ID | 5511 |
|---|---|
| Other Names | Nuclear inhibitor of protein phosphatase 1, NIPP-1, Protein phosphatase 1 regulatory inhibitor subunit 8, Activator of RNA decay, 3.1.4.-, ARD-1, PPP1R8, ARD1, NIPP1 |
| Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-NIPP1 / PPP1R8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PPP1R8 |
|---|---|
| Synonyms | ARD1, NIPP1 |
| Function | Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre- mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation. |
| Cellular Location | Nucleus. Nucleus speckle. Note=Primarily, but not exclusively, nuclear |
| Tissue Location | Ubiquitously expressed, with highest levels in heart and skeletal muscle, followed by brain, placenta, lung, liver and pancreas. Less abundant in kidney. The concentration and ratio between isoforms is cell-type dependent. Isoform Alpha (>90%) and isoform Beta were found in brain, heart and kidney. Isoform Gamma is mainly found in B-cells and T-lymphocytes, and has been found in 293 embryonic kidney cells. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 341.00
Cat# AF1732a
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