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Goat Anti-NOVA1 Antibody

Peptide-affinity purified goat antibody

  • IHC - Goat Anti-NOVA1 Antibody AF1740a
    AF1740a (2.5 µg/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
  • WB - Goat Anti-NOVA1 Antibody AF1740a
    AF1740a (0.01 µg/ml) staining of Human Breast Cancer lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • WB - Goat Anti-NOVA1 Antibody AF1740a
    HEK293 overexpressing NOVA1 (RC210407) and probed with AF1740a (mock transfection in first lane), tested by Origene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51513
Other Accession NP_006482, 4857
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 52056 Da
Additional Information
Gene ID 4857
Other Names RNA-binding protein Nova-1, Neuro-oncological ventral antigen 1, Onconeural ventral antigen 1, Paraneoplastic Ri antigen, Ventral neuron-specific protein 1, NOVA1
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-NOVA1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NOVA1
Function May regulate RNA splicing or metabolism in a specific subset of developing neurons.
Cellular Location Nucleus.
Tissue Location Brain.
Research Areas
Citations (0)

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This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.


Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients. Alkelai A, et al. Psychopharmacology (Berl), 2009 Oct. PMID 19680635.
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. Vasan RS, et al. JAMA, 2009 Jul 8. PMID 19584346.
Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. Anney RJ, et al. Am J Med Genet B Neuropsychiatr Genet, 2008 Dec 5. PMID 18951430.
Paraneoplastic antibody during follow-up of a patient with anti-Ri-associated paraneoplastic neurological syndrome. Stich O, et al. Acta Neurol Scand, 2009 May. PMID 18822086.
Post-transcriptional regulation of neuro-oncological ventral antigen 1 by the neuronal RNA-binding proteins ELAV. Ratti A, et al. J Biol Chem, 2008 Mar 21. PMID 18218628.

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$ 325.00
Cat# AF1740a
(40 western blots)
Availability: 7-10 days
Bulk Size
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